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Received:December 07, 2021 Published Online:June 20, 2022
Received:December 07, 2021 Published Online:June 20, 2022
中文摘要: 结核分枝杆菌（MTB）感染是目前严重危害人类健康的传染病之一，以引起肺结核最为常见，尽早识别、诊断与有效治疗对于控制MTB播散至关重要。结核分枝杆菌/利福平耐药实时荧光定量核酸扩增检测技术(Xpert MTB/RIF)是一种新兴的诊断技术，可在检测MTB同时判断是否出现利福平耐药，具有较高的敏感性及特异性。本文将对该检测方法在肺结核、肺外结核、儿童结核、HIV感染及自身免疫系统疾病结核患者以及利福平耐药性检测方面作一综述。
Abstract:Infection of mycobacterium tuberculosis (MTB) is one of the most serious infectious diseases endangering human health. Pulmonary tuberculosis is the major type. In order to control the spread of MTB, it’s important to identify early, diagnosis early and treat effectively. Xpert MTB/RIF can detect MTB and rifampicin resistance at the same time in high sensitivity and specificity. This review is aimed to review the application of this method in detecting of pulmonary tuberculosis, extrapulmonary tuberculosis, tuberculosis in children, HIV and autoimmune system diseases combined with tuberculosis, and rifampicin resistance.
keywords: Mycobacterium tuberculosis Tuberculosis Xpert Mycobacterium Tuberculosis/Rifampicin, Xpert MTB/RIF Rifampin Resistance
文章编号： 中图分类号：R52 文献标志码：A
基金项目:陕西省重点研发计划项目（2019SF-151）
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