Abstract:Hyperlipidemic acute pancreatitis (HLAP) is usually caused by elevated serum triglyceride levels. Compared with acute pancreatitis (AP) caused by other causes, HLAP has the characteristics of rapid progress, severe, many complications and easy recurrence. It is closely related to the direct or indirect damage of free fatty acids and inflammatory factors produced by the decomposition of serum triacylglycerol to the pancreas and multiple organs of the whole body. Blood purification (BP) treatment can quickly and effectively reduce the levels of serum triacylglycerol and inflammatory mediators, block the cascade reaction of inflammatory factors, and improve the condition. This method also plays a certain role in regulating water electrolyte and acid-base balance disorder. At present, the use of blood purification in the treatment of HLAP has been recognized by most scholars. This paper reviews the research progress of BP in the treatment of HLAP at home and abroad in recent years.