Abstract:Objective To observe the clinical application of autogenous auricular cartilage free transplantation in the treatment of severe inverted nipple. Methods A total of 120 patients with severe inverted nipple treated from January 2014 to January 2020 were randomly divided into control group and experimental group (n=60,each).The autogenous auricular cartilage free transplantation was performed in experimental group,and the skin flap,suture and physical traction were conducted in control group.The operation time,degree of surgical trauma (blood loss,wound size),hospital stay,improvement of nipple shape and function after operation,satisfaction of patients and quality of life were comprehensively evaluated in two groups. Results Compared with control group,the operation time,blood loss,wound size and hospital stay significantly decreased in experimental group (all P<0.01).The improvement scores of nipple shape and function,the satisfaction scores of treatment process,postoperative function and scar healing in experimental group were significantly higher than those in control group (all P<0.01).After operation,the World Health Organization Quality of life Instrument-Short Form(WHOQOL-BREF) scores were significantly higher than those before operation in two groups and were significantly higher in experimental group than those in control group (all P<0.01). Conclusion In the treatment of severe inverted nipple,free transplantation of autogenous auricular cartilage can significantly shorten the operation time,reduce the trauma degree of operation,the hospitalization time,and increase the improvement degree of nipple shape and function and the satisfaction score of the patients,the effect is ideal.