Abstract:Objective To compare the clinical effect of transversus abdominis plane block and sacral block in laparoscopic high ligation of hernia sac under general anesthesia in children. Methods A total of 92 children received laparoscopic appendectomy under general anesthesia from January 2018 to September 2019 were selected as study objects and randomly divided into transverus abdominis plane block group (n=46,received general anesthesis plus transverus abdominis plane block anesthesia) and sacral block group (n=46,received general anesthesis plus sacral block anesthesia).The operation related conditions,intraoperative monitoring indexes,postoperative self-control sufentanil consumption(add on the basic amout),pain FLACC score,postoperative anesthesia adverse reactions and gastrointestinal function recovery were compared and analyzed between two groups. Results The postoperative wake-up time and time out of the observation room of transverus abdominis plane block group were shorter than those of sacral block group (all P<0.01).At the beginning and end of the operation,the mean arterial pressure of transverus abdominis plane block group was higher than those of the sacral block group (all P<0.05),while the heart rate of transverus abdominis plane block group was lower than that of the sacral block group(all P<0.05).Within 6 hours after operation,the additional consumption of sufentanil and FLACC score in transverus abdominis plane block group were higher than those in sacral block group(all P<0.05).There was no difference in the additional consumption of sufentanil and FLACC score at the three time points of 12 h,18 h and 24 h after operation between the two groups and no significant difference in the incidence of postoperative complications between the two groups (all P>0.05). The time of catheter removal and anal exhaust in transverus abdominis plane block group were lower than those in sacral block group (all P<0.01). Conclusions There are advantages and disadvantages of transverus abdominis plane block and sacral block in children′s laparoscopic high ligation of hernia sac under general anesthesia.The application of transverus abdominis plane block is conducive to the maintenance of vital signs,postoperative wake-up and the recovery of gastrointestinal function, but the application of sacral block has better short-term analgesic effect,which can reduce the amount of postoperative anesthetic drugs.