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中国临床研究:2018,31(3):380-383
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地佐辛在剖宫产术后集束化镇痛措施中的作用
(1.陕西省人民医院麻醉科,陕西 西安 710068;2.西安交通大学第一附属医院急诊科,陕西 西安 710061;3.陕西省妇幼保健院麻醉科,陕西 西安 710061)
Effect of dezocine in the bundle for analgesia after cesarean section
摘要
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投稿时间:2017-09-15   网络发布日期:2018-03-20
中文摘要: 目的 探讨地佐辛注射液在剖宫产术后集束化镇痛措施中的作用。方法 选择腰-硬联合麻醉下行剖宫产术的产妇100例,ASAⅠ或Ⅱ级,随机均分为两组:地佐辛组和对照组。两组采用的集束化镇痛措施包括:术中麻醉平面达T6,胎儿娩出后给予静脉和硬膜外镇痛负荷量,术后采用静脉自控镇痛(PCIA)模式进行静脉镇痛;地佐辛组加用地佐辛作静脉镇痛,对照组未加地佐辛,于术后即刻,6、12、24、48 h时行静息时宫缩痛视觉模拟评分(VAS)、活动时伤口VAS评分、Ramsay镇静评分;记录产妇术后排气时间、满意度及不良反应的发生情况。结果 最终有93例产妇参加本研究。与对照组比较,术后24 h 地佐辛组产妇静息时宫缩痛VAS评分降低[(2.3±1.3)分 vs (2.9±1.2)分,P<0.05],术后即刻镇静评分降低[(2.7±0.8)分 vs (2.0±0.7)分,P<0.05],排气时间缩短[(22.0±2.9)h vs (23.6±2.6)h,P<0.05],满意度较高 (61.7% vs 34.8%,P<0.01);两组间并发症的发生率无显著差异(P>0.05)。结论 在剖宫产术后集束化镇痛措施中加入地佐辛静脉用药,可降低宫缩痛,缩短排气时间,提高满意度,且未增加不良反应。
Abstract:Objective To investigate the effect of dezocine in the bundle for analgesia after cesarean section.? Methods A hundred cases of puerperae who received cesarean section under combined spinal-epidural anesthesia at ASA Ⅰ orⅡ were divided into dezocine group and control group (50 cases each). Both groups were given bundle for analgesia, including that the anesthesia level was T6 during the operation, the intravenous and epidural analgesia were given with bolus doses after the operation, and the patient-controlled intravenous analgesia(PCIA) was used in the postoperative intravenous analgesia. The dezocine group was given dezocine as extra intravenous analgesia while the control group was not. The visual analogue scale(VAS) at rest and active time and Ramsay sedation score were recorded immediately after operation and at 6, 12, 24, 48 hours after operation. The postoperative evacuation time, degree of satisfaction and the situation of adverse reaction were recorded.? Results There were 93 puerperae participated in this research, 47 cases in dezocine group and 46 cases in control group. Compared with control group, the rest time VAS was lower (2.3±1.3 vs 2.9±1.2, P<0.05) at 24 hours after the operation, the evacuation time was shorter [(22.0±2.9)h vs (23. 6±2. 6)h, P<0.05], and the degree of satisfaction was higher (61.7% vs 34.8%, P<0.05) in dezocine group. There was no significant difference in the incidence of complications between the two groups (21. 3% vs 28. 3%, P>0.05).? Conclusion Using dezocine in the bundle for analgesia after cesarean section could reduce the uterine contraction pain, shorten the evacuation time and improve the satisfaction without extra adverse reactions.
文章编号:     中图分类号:R 64,R 719.8    文献标志码:B
基金项目:陕西省社会发展科技攻关项目(2016SF-035)
引用文本:
常建华,金梅梅,张文娟,等.地佐辛在剖宫产术后集束化镇痛措施中的作用[J].中国临床研究,2018,31(3):380-383.

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