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Received:May 28, 2024 Published Online:May 20, 2025
Received:May 28, 2024 Published Online:May 20, 2025
中文摘要: 在 Krüppel样因子 9（KLF9）是一种含有三个 Cys2His2型锌指结构的转录因子，具有包括调控胚胎发育、细胞增殖、凋亡、分化、转移和侵袭等广泛的生物学功能。本文讨论了 KLF9的生物学特征、在不同肿瘤中的表达情况和调控机制，并展望了未来的应用前景。
Abstract:Krüppel.like factor 9 (KLF9) is a transcription factor containing three Cys2His2 zinc finger structures with a wide range of biological functions, including regulation of embryonic development, cell proliferation, apoptosis, differentiation, metastasis and invasion. This article discusses the biological features, expression in different tumors and regulatory mechanisms of KLF9, and the prospects for its future applications.
keywords: Krüppel.like factor 9 Transcription factor Tumors Regulatory mechanisms Gastric cancer Endometrial cancer Breast cancer Pancreatic cancer
文章编号： 中图分类号：R363 文献标志码：A
基金项目:国家自然科学基金面上项目（81372137）
| Author Name | Affiliation |
| LIU Cunyu, KONG Xia, WANG Shiqi, HE Zhiwei | China-America Cancer Research Institute, Guangdong Medical University, Dongguan, Guangdong 523808, China |
| Author Name | Affiliation |
| LIU Cunyu, KONG Xia, WANG Shiqi, HE Zhiwei | China-America Cancer Research Institute, Guangdong Medical University, Dongguan, Guangdong 523808, China |
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