Abstract:Bloodstream infection (BSI) is an inflammatory reaction caused by various pathogens invading into human blood circulation. In severe cases, it can lead to multiple organ failure and death. Up to now, blood culture remains the gold standard for diagnosing BSI. Antibiotics are commonly used in clinical treatment for BSI. In recent years, with the use of a large number of broad-spectrum antibiotics, and the widespread development of various invasive diagnosis and treatment operations, the incidence of BSI has gradually increased. At present, the current status of BSI in intensive care units，the types and drug resistance of pathogenic bacteria that cause BSI, how to quickly identify the types of pathogenic bacteria in patients, and the treatment options for BSI in critically ill patients have received extensive attention. This article provides a review of the above issues.