Abstract:Objective To analyze the changes of blood indicators in pregnant women with different degrees of hypertensive disorders of pregnancy (HDP). Methods A retrospective study was conducted on the clinical data of the patients with HDP admitted to the First Hospital of Shanxi Medical University from July 2017 to July 2022, and the patients were divided into HDP group, mild pre-eclampsia (PE) group (without severe PE) and severe PE group (n=75, each). Another 75 normal pregnant women in the same period were randomly selected as control group. The levels of blood indicators were compared among four groups. Results Compared with those in control group, neutrophil count, neutrophil/lymphocyte ratio (NLR), platelet distribution width (PDW), mean platelet volume (MPV), fibrinogen (FIB), creatinine, uric acid and urea nitrogen levels increased statistically in the order of HDP group, mild PE group and severe PE group (P＜0.05), and activated partial thrombin time (APTT), prothrombin time (PT) and antithrombin Ⅲ (AT-Ⅲ) decreased successively (P＜0.05). Conclusion HDP can affect the concentrations of blood indexes of patients, which can be used to evaluate the progression and severity of the disease so as to implement the corresponding preventive measures in advance.