Abstract:Objective To study the acceptance of advanced care planning（ACP） and its influencing factors in elderly leukemia patients, to provide reference for the implementation and promotion of ACP in elderly patients. Methods Using convenient sampling method, 217 elderly patients with acute myeloid leukemia who received chemotherapy in the First Affiliated Hospital with Nanjing Medical University from January 2019 to December 2021 were selected as the research objects. The subjects were investigated with self-made basic information questionnaire, ACP questionnaire, self-made acute myeloid leukemia questionnaire, Chinese version Eysenck Personality Questionnaire short form scale, etc. The influencing factors of ACP was anayzed. Results The ACP acceptance score of 217 elderly patients with acute myeloid leukemia was（69.31±9.97）, and the average score of each item was（3.65±0.52）. Multiple linear regression results showed that education level, place of residence, marriage, number of chemotherapy, bereavement experience, understanding of disease,personality traits are the factors that affect the acceptance of ACP in elderly patients with acute myeloid leukemia（P<0.05）. ConclusionThe acceptance of ACP in elderly patients with acute myeloid leukemia in Nanjing is at a high level, which is affected by many factors. Relevant departments should take measures to improve the acceptance of ACP in elderly patients.