本文已被:浏览 571次 下载 309次
Received:January 10, 2022 Published Online:September 20, 2022
Received:January 10, 2022 Published Online:September 20, 2022
中文摘要: 目的 探讨超声引导定位技术在乳腺肿瘤早期诊断中的应用价值。方法 收集2014年1月至2017年12月于陕西省肿瘤医院经超声引导定位活检的乳腺肿瘤病例626例,分析超声特征与临床病理参数的相关性。结果 确诊乳腺癌252例,癌前病变53例,良性病例321例,其中癌前病变及乳腺癌为48.72%(305/626);导管内癌11例,浸润性癌241例;0~〖KG-*4〗Ⅰ、Ⅱ、Ⅲ期分别为87例、126例、39例,0~〖KG-*4〗Ⅰ期占34.52%(87/252)。肿瘤直径、边界、形态、内部回声、钙化特点、血流信号、包膜、腋窝淋巴结、BI-RADS分级等超声特征在良恶性病变中差异有统计学意义(P<0.05)。不同肿瘤直径组超声形态、内部回声、钙化灶、血流信号及BI-RADS分级差异有统计学意义(P<0.05);不同TNM分期组超声形态、内部回声、BI-RADS分级差异有统计学意义(P<0.05)。BI-RADS在有无淋巴结转移组、是否浸润性癌组,差异有统计学意义(P<0.05)。包膜特征在是否浸润性癌组差异有统计学意义(P<0.05)。超声形态在不同肿瘤组织学分组中差异无统计学意义(H=2.086,P=0.353)。结论 超声引导定位技术在乳腺肿瘤早期诊断中具有重要临床价值。
Abstract:Objective To investigate the clinical value of ultrasound-guided localization in the early diagnosis of breast tumors. Methods A total of 626 cases of breast tumors with ultrasound-guided localization biopsy were collected in Shaanxi Cancer Hospital from January 2014 to December 2017 to analyze the correlation between ultrasonographic features and clinicopathological parameters. Results There were 252 cases of breast cancer (11 cases of intraductal carcinoma and 241 cases of invasive carcinoma), 53 cases of precancerous lesions and 321 cases of benign lesions, and precancerous lesions and breast cancer accounted for 48.72% (305/626). The pathological stages were stage 0-Ⅰ in 87 cases, stage Ⅱ in 126 cases and stage Ⅲ in 39 cases, with 34.52% of stage 0-Ⅰ (87/252). There were significant differences in tumor diameter, boundary, shape, internal echo, calcification characteristics, blood flow signal, capsule, axillary lymph nodes and BI-RADS grading between benign and malignant lesions (P<0.05). There were statistical differences in tumor morphology, internal echo, calcification and blood flow signal among the tumors with different diameters (P<0.05) and in tumor morphology, internal echo and BI-RADS grading in the tumors at different TNM stages (P<0.05). There were significant differences in BI-RADS grading between the metastatic and invasive tumors and those without lymph node metastasis and invasion (P<0.05). There were significant differences in the tumor cell envelope characteristics between the invasive carcinoma group and the non-invasive carcinoma group (P<0.05). There was no significant differece in the ultrasonic morphological characteristics among different histological grades of breast carcinoma (H=2.086, P=0.353). Conclusion Ultrasound-guided localization has important clinical value in the early diagnosis of breast tumors.
keywords: Breast tumors Ultrasound-guided localization Early diagnosis Ultrasonic morphology BI-RADS grading
文章编号: 中图分类号:R737.9 文献标志码:A
基金项目:陕西省卫健委医学科研项目(2018D029);陕西省重点研发计划(2022SF-010)
引用文本: