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Received:September 17, 2021 Published Online:May 20, 2022
Received:September 17, 2021 Published Online:May 20, 2022
中文摘要: 目的 探究悬灸联合自拟筋骨止痛膏对膝骨性关节炎（KOA）的疗效。方法 筛选2019年5月到2021年5月安徽中医药大学第二附属医院符合标准的KOA患者70例，随机分为对照组（常规治疗）和观察组（悬灸联合自拟筋骨止痛膏治疗），各35例，对照组脱落1例，最终纳入对照组34例，观察组35例。比较两组干预前后西安大略和麦克玛斯特大学骨关节炎指数（WOMAC）评分、C反应蛋白（CRP）水平、抑郁自评量表（SDS）评分、焦虑自评量表（SAS）评分、生存质量测定量表简表（QOL-BREF）评分变化情况。结果 干预后，两组WOMAC评分、血CRP、SDS评分、SAS评分、QOL-BREF评分均较干预前改善（P<0.05），且观察组改善优于对照组（P<0.05）。结论 悬灸联合自拟筋骨止痛膏干预膝骨性关节炎患者疗效确切，可改善患者负性情绪，提高生存质量。
Abstract:Objective To explore the effect of suspended moxibustion plus self-made Jingu Zhitong Ointment on the patients with knee osteoarthritis(KOA). Methods Seventy KOA patients admitted to the Second Affiliated Hospital of Anhui University of Chinese Medicine from May 2019 to May 2021 were selected and randomly divided into control group［treated with routine treatment, n =34 (one case fell off) ］ and observation grouP(treated with suspension moxibustion plus self-made Jingu Zhitong Ointment, n =35). The changes of Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), blood C-reactive protein (CRP) levels, self-rating depression scale (SDS), self-rating anxiety scale (SAS) and Quality of Life Assessment Instrument Brief Version (QOL-BREF) scales were observed and statistically compared between two groups before and after intervention. Results After intervention, WOMAC score, blood CRPlevel, SDS, SAS and QOL-BREF scores significantly improved compared with those before intervention in both groups (P<0.05). In observation group, the improvement of the above indexes was superior to those in control grouP(P<0.05). Conclusion Suspension moxibustion combined with self-made Jingu Zhitong Ointment has a definite effect on patients with knee osteoarthritis, which can relieve the patient's negative mood and improve their quality of life.
keywords: Suspended moxibustion Self-made Jingu Zhitong Ointment Knee osteoarthritis Negative emotions Quality of life
文章编号： 中图分类号： 文献标志码：B
基金项目:安徽省高校自然科学研究重点项目（KJ2016A395）
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