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Received:July 15, 2021 Published Online:February 20, 2022
Received:July 15, 2021 Published Online:February 20, 2022
中文摘要: 目的 探讨超声造影(CEUS)联合超声弹性成像技术(UE)对甲状腺乳头状癌(PTC)淋巴结转移的诊断价值。方法 选择2018年1月至2021年1月在华中科技大学协和深圳医院就诊的80例PTC患者为研究对象,所有患者均经CEUS、UE及病理检查确诊,根据PTC结节是否发生淋巴结转移分为转移组(37例)和非转移组(43例)。观察比较两组患者PTC结节UE弹性评分及弹性应变率、CEUS增强特征及相关参数,并分析CEUS联合UE诊断PTC淋巴结转移效能。结果 两组患者弹性评分比较差异无统计学意义(P>0.05);转移组弹性应变率明显高于非转移组(P<0.05)。两组患者增强模式、流入强度、流出强度比较差异无统计学意义(P>0.05);两组增强类型比较,差异有统计学意义(P<0.05)。两组患者达峰时间(TTP)、平均通过时间(MTT)、曲线下面积(AUC)比较差异无统计学意义(P>0.05),转移组峰值强度(PI)明显高于非转移组(P<0.05)。CEUS联合UE对PTC淋巴转移的敏感性、特异性及准确性分别为95.7%、92.2%和93.0%,高于单项UEUS或UE检测。结论 CEUS联合UE对PTC淋巴转移具有较好的诊断价值。
Abstract:Objective To investigate the value of contrast-enhanced ultrasound (CEUS) combined with ultrasonic elastography (UE) in the diagnosis of lymph node metastasis of thyroid papillary carcinoma (PTC). Methods Eighty PTC patients admitted to Union Shenzhen Hospital from January 2018 to January 2021 were selected as the research subjects. All patients were confirmed by CEUS, UE and pathological examination. The patients were divided into metastatic group (n=37) and non-metastatic group (n=43) according to whether the patients had lymph node metastasis. The UE elasticity score, elastic strain rate, CEUS enhancement characteristics and related parameters of PTC nodules were observed and compared between two groups to analyze the diagnostic efficiency of CEUS combined with UE in lymph node metastasis of PTC. Results There was no significant difference in elasticity score between two groups (P>0.05), and the elastic strain rate in metastatic group was significantly higher than that in non-metastatic group (P<0.05). There was no significant difference in CEUS enhancement mode, inflow intensity and outflow intensity between two groups (P>0.05), but there was significant difference in enhancement type between two groups (P<0.05). There was no significant difference in time to peak (TTP), mean transit time (MTT) and area under the curve (AUC) between two groups (P>0.05).The peak intensity (PI) in metastatic group was significantly higher than that in non-metastatic group (P<0.05). The sensitivity, specificity and accuracy of CEUS combined with UE for PTC lymphatic metastasis were 95.7%, 92.2% and 93.0%, respectively and were higher than those by UEUS or UE alone. Conclusion CEUS combined with UE has good diagnostic value for PTC lymph node metastasis.
keywords: Papillary thyroid carcinoma Lymph node metastasis Contrast-enhanced ultrasound Ultrasonic elastography Diagnosis
文章编号: 中图分类号:R736.1 R445.1 文献标志码:B
基金项目:
Author Name | Affiliation |
TANG Wen-jing, ZHU Ting, FANG Jing | Department of Ultrasound, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen,Guangdong 518000, China |
Author Name | Affiliation |
TANG Wen-jing, ZHU Ting, FANG Jing | Department of Ultrasound, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen,Guangdong 518000, China |
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