Abstract:Objective To evaluate the consistency of controlled attenuation parameter (CAP) by transient elastography（HepaTest）and color Doppler ultrasound in the diagnosis of nonalcoholic fatty liver disease (NAFLD) and the correlation between CAP and clinical indicators.Methods The patients admitted to Luohu District People′s Hospital of Shenzhen from January 2020 to December 2020 were selected.Hepatest and upper abdominal ultrasonography were simultaneously performed for all patients.Hepatest was used to detect CAP for liver fat and liver stiffness measurement (LSM).The data of age,gender,BMI and clinical biochemical indexes were collected,Kappa test was used to evaluate the consistency of CAP and ultrasound results.Multiple linear regression analysis and regression equation were used to evaluate the related factors affecting CAP.Results Among 330 patients enrolled,there were 223 males,with an average age of (37±10) years.A total of 103 cases (31.21%) of fatty liver were detected by abdominal color ultrasound, and 124 cases of fatty liver were detected by HepaTest. Using color ultrasound as the standard, the accuracy of HepaTest in detecting fatty liver was 93.6%, the sensitivity was 100%, the specificity was 90.7%, the positive predictive value was 83.1%, and the negative predictive value was 100%.CAP was highly consistent with the results of color ultrasound (Kappa coefficient=0.860,P<0.01).Multiple linear regression analysis showed that CAP（Y） was significantly linearly correlated with BMI and UA,and the regression equation was Y=122.618+3.751×BMI+0.052×UA.conclusions In the diagnosis of fatty liver,CAP is consistent with color Doppler ultrasound and positively correlated with BMI and UA.