Abstract:Objective To analyze the clinical efficacy and application value of mixed reality technology in retroperitoneal tumor surgery.Methods Eight patients with retroperitoneal tumor treated from September 2018 to July 2020 were selected,including 3 males and 5 females with a mean age of （44.4±18.6）years old(ranging from 24 to 68).The tumor volume was 83.3 to 1 351.6 (699.9±493.8) ml,and the course of disease was 3-96(24.4±32.3) weeks.Of 3 benign and 5 malignant tumors,there were 1 case of schwannoma,1 case of neurofibroma,1 case of inflammatory myofibroblastoma,1 case of extraosseous osteosarcoma,2 cases of malignant schwannomas,1 case of leiomyosarcoma and 1 case of liposarcoma.Mixed reality technology was used to analyze tumor size,adjacent structure and anatomical location.The intraoperative blood loss and the operation time were recorded.Results The operation time was 80-280 (165.0±67.3) min,and the intraoperative blood loss was 500-2 000 (1 062.5±616.3) ml.All patients were successfully operated according to the preset operation flow.The blood vessels and nerves adjacent to the tumor were well protected without obvious evidence of damage.All patients were followed up for 1-18 (7.9±6.2) months,and no tumor recurrence or metastasis was found in 8 cases.conclusions For the patients with retroperitoneal tumors,mixed reality technology can be used as an auxiliary means for preoperative design,doctor-patient communication and intraoperative guidance to avoid damaging important anatomical structures adjacent to the tumor.