Abstract:ObjectiveTo analyze the associations of serum hemoglobin (Hb)and albumin (ALB) levels with the prognosis in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) to provide new ideas in prognostic evaluation of patients with AECOPD.MethodsThe clinical data of 106 patients with AECOPD from March 2018 to October 2019 were analyzed retrospectively.The patients were divided into survival group (n=87) and death group(n=19) according to the prognosis.The general situations questionnaire was designed to record the general data (gender,age,course of disease),pulmonary function indexes ［forced expiratory volume in first second (FEV1),forced vital capacity (FVC),FEV1/FVC］,blood gas indexes ［partial pressure of blood oxygen (PaO2),partial pressure of carbon dioxide (PaCO2)］ and serum indexes(Hb,ALB) in two groups.Spearman method was used to analyze the associations of Hb and ALB with the prognosis of patients with AECOPD.ResultsFEV1/FVC and PaO2 in survival group were higher than those in death group,and PaCO2 was lower than that in death group (P<0.01);HB level in survival group was lower than that in death group［(146.98 ± 15.64) g /L vs (187.95±18.64）g/L,P＜0.01）］,and ALB level in survival group was higher than that in death group ［（39.65±5.21）g/L vs (31.25±4.01）g/L,P<0.01 ］.Spearman correlation analysis showed that Hb level was negatively correlated with the prognosis of AECOPD patients (r=-0.700,P<0.05),and ALB level was positively correlated with the prognosis of AECOPD patients (r=0.543,P<0.05).ConclusionThe levels of Hb and ALB are closely related to the prognosis of patients with AECOPD and can effectively reflect the severity of the disease.Higher Hb level and lower ALB level are correlated with the worse prognosis of patients.