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中国临床研究英文版:2020,33(8):1087-1089,1093
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小儿轻度胃肠炎伴热性和良性惊厥的对比
(唐山市妇幼保健院儿科,河北 唐山063000)
Febrile seizures and benign convulsion in children with mild gastroenteritis
(Department of Pediatrics,Tangshan Maternal and Child Health Hospital,Tangshan,Hebei 063000,China)
摘要
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Received:December 16, 2019   Published Online:August 20, 2020
中文摘要: 目的 研究小儿轻度胃肠炎伴热性惊厥和良性惊厥的临床特点。方法 回顾性分析2017年1月至2018年12月唐山市妇幼保健院126例小儿轻度胃肠炎伴发热惊厥与良性惊厥患儿的临床资料,将其分为热性惊厥组(n=61)和良性惊厥组(n=65),分析比较两组患儿人口学特征、临床特征、实验室检查结果及胃肠炎病毒抗原类型。结果 良性惊厥组、热性惊厥组平均年龄分别为23.0、19.6个月,两组的入院时间均主要在秋冬季,热性惊厥组的热性惊厥家族史患儿多于良性惊厥组(37.7% vs 16.9%,P<0.05);与热性惊厥组相比,良性惊厥组胃肠道症状开始到首次发作的时间更长,惊厥更易复发及丛集性惊厥发生率更高(P<0.05,P<0.01)。良性惊厥组的血清钠高于热性惊厥组,天冬氨酸氨基转移酶(AST)、白细胞计数低于热性惊厥组(P<0.01);良性惊厥组的诺如病毒抗原高于热性惊厥组(P<0.01)。结论 两组患儿均预后良好。胃肠炎伴良性惊厥,入院后24 h内更易复发和发生丛集性惊厥。胃肠炎伴热性惊厥可能多为轮状病毒引起,轻度胃肠炎伴良性惊厥可能多为诺如病毒引起。
中文关键词: 胃肠炎  良性惊厥  热性惊厥  儿童  诺如病毒
Abstract:ObjectiveTo study the clinical characteristics of febrile convulsion and benign convulsion in children with mild gastroenteritis.MethodsThe clinical data of 126 children with mild gastroenteritis complicated with febrile convulsion(FC group,n=61) and benign convulsion(BC group,n=65) were retrospectively analyzed,who were treated in Tangshan maternal and child health hospital from January 2017 to December 2018.The clinic characteristics of patients were analyzed and compared between two groups.ResultsThe average ages were 23 and 19.6 months respectively in BC group and FC group.The family history of febrile convulsion in FC group was significantly higher than that in BC group(37.7% vs 16.9%,P<0.05).The admission time was mainly in autumn and winter for both groups.Compared with FC group,the time from the beginning of gastrointestinal symptoms to the first convulsion seizure was significantly prolonged,with more frequent recurrence and cluster convulsions in BC group (P<0.05,P<0.01).Compared with BC group,serum sodium and norovirus antigen decreased,and AST and WBC count increased statistically in FC group (P<0.01).ConclusionsThere are good prognosis in both groups,even there were some differences in family history,levels of serum sodium,AST,leukocyte count,etc.Gastroenteritis with benign convulsion is more likely to recur with cluster convulsions within 24 hours after admission.Gastroenteritis with febrile convulsion may be caused by rotavirus,and mild gastroenteritis with benign convulsion may be caused by norovirus.
文章编号:     中图分类号:    文献标志码:B
基金项目:河北省卫生厅科研基金项目(20181345)
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