Abstract:ObjectiveTo analyze the clinical characteristics and the effect of interventional therapy in patients with coronary artery spasm(CAS) angina.MethodsBased on the complete information of 27 patients with vasospastic angina (VSA) from January 2010 to April 2018,the clinical characteristics and interventional therapy were analyzed retrospectively.ResultsThere were 16 (59.26%) cases of angina attack at midnight and 16 (59.26%) cases of inferior wall ST segment elevation during angina attacks confirmed by body surface electrocardiographic (ECG) or dynamic ECG.Coronary angiography showed significant stenosis in 11 patients (40.74%) and no obvious stenosis in 16 patients (59.26%).In 11 cases with significant stenosis,6 cases of right coronary artery(RCA) stenosis were treated by PCI,including 5 cases with stents implanted in the left anterior descending artery and 1 case in the left circumflex branch.In 4 cases after PCI,angina pectoris were confirmed not to result from the coronary spasm with PCI.There were no statistical differences in age,blood lipid (LDL-C),incidences of hypertension,smoking,diabetes and ST segment elevation of ECG between the patients with obvious stenosis and the patients without significant stenosis (P>0.05).All patients received calcium channel blockers and nitrate on the basis of controlling risk factors,and angina pectoris was well controlled in 23 patients during hospitalization.One month after discharge,there were 4 patients with angina attacks which were controlled when nicorandil was added.ConclusionsCoronary spasm angina is more common in the patients with RCA without significant stenosis and is mainly controlled by drugs.