Abstract:Objective To investigate the clinical effect of Dahuang (Radix et Rhizoma Rhei) combined with enteral nutrition for severe acute pancreatitis (SAP) in early stage. Methods A total of 45 patients with SAP who received treatment from January 2014 to December 2017 were divided into observation group (n=25) and control group (n=20). The observation group received perfusion of Dahuang and enteral nutrition solution through enteral nutrition tube, and the control group was treated by enteral nutrition tube perfusion of Dahuang. The time of relieving abdominal pain and distention, the time of recovery of gastrointestinal function and biochemical indices (such as hemodiastase) reactions were compared between two groups. Results Compared with control group, the level of hemodiastase, blood glucose and C-reactive protein (CRP) were significant lower and level of serum calcium was significant higher in observation group after one week of treatment (all P<0.05). The time of relieving abdominal pain and distention and the time of gastrointestinal function recovery in observation group were significant shorter than those in control group[(3.25±0.42) d vs (4.75±0.97) d, (3.35±0.53) d vs (4.60±0.86) d, (3.10±0.45) d vs (4.52±0.73) d, all P<0.05]. Conclusion Dahuang combined with enteral nutrition in the treatment of SAP is an effective and safe treatment method.