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投稿时间：2024-03-16 网络发布日期：2025-02-20
投稿时间：2024-03-16 网络发布日期：2025-02-20
中文摘要: 急性胰腺炎（AP）是一种胰腺炎症性疾病，临床上有约1/5的轻症急性胰腺炎（MAP）患者可能会最终发展成为重症急性胰腺炎（SAP），SAP患者病情进展迅速，并可能导致全身炎症反应综合征和多器官功能衰竭，从而影响患者生命安全。尽早预测AP病情严重程度及预后对于为患者提供相应的治疗至关重要。血清生物学指标具有检测便捷、获取快速、可重复等优势，作为早期评估AP病情严重程度的指标具有可观的应用前景。故本研究就AP病情及预后的血清生物学预测指标作一综述。
中文关键词: 急性胰腺炎 重症急性胰腺炎 肿瘤坏死因子α 降钙素原 血小板计数/淋巴细胞计数比值
Abstract:Acute pancreatitis (AP) is an inflammatory disease of the pancreas. About one-fifth of patients with mild acute pancreatitis (MAP) may eventually develop severe acute pancreatitis (SAP). SAP progress rapidly and may lead to systemic inflammatory response syndrome and multiple organ failure, thus affecting the safety of patients. Early prediction of the severity and prognosis of AP is essential to provide appropriate treatment for patients. Serum biological indicators have the advantages of convenient detection, rapid acquisition and repeatability, and have considerable application prospects as indicators for early assessment of the severity of AP. This article summarizes the serum biological predictors for the condition and prognosis of AP.
keywords: Acute pancreatitis Severe acute pancreatitis Tumor necrosis factor alpha Procalcitonin Platelet-to-lymphocyte ratio
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附件
| Author Name | Affiliation |
| GE Zhiwen, NIE Shinan, ZHANG Wei, SUN Zhaorui, FENG Jing | Nanjing Medical University, Nanjing, Jiangsu 211166, China |
引用文本：
葛志文,聂时南,张炜,等.急性胰腺炎病情严重程度及预后的预测指标[J].中国临床研究,2025,38(2):320-324.
葛志文,聂时南,张炜,等.急性胰腺炎病情严重程度及预后的预测指标[J].中国临床研究,2025,38(2):320-324.