Abstract:Sepsis is a common disease, with high incidence, high mortality, and high cost, seriously threatening the health of patients. Lysozyme, a kind of glycosidase, is an important protein with broad-spectrum antibacterial activity in the granules of neutrophils and macrophages. It can not only stimulate the phagocytic activity of polymorphonuclear cells, leukocytes, and macrophages, but also has high specificity and low toxicity, playing an important role in the innate immune response against bacterial invasion. Currently, many clinical studies have shown a close relationship between sepsis and lysozyme. This article provides an overview of the latest research progress on lysozyme and sepsis.