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中国临床研究:2024,37(7):1120-1123
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维奈克拉联合阿扎胞苷及高三尖杉酯碱治疗复发/难治急性髓系白血病的疗效及机制
(河南科技大学临床医学院,河南 洛阳 471000)
Efficacy and mechanism of venetoclax combined with azacitidine and homoharringtonine in treatment of relapsed/refractory acute myeloid leukemia
(School of Clinical Medicine, Henan University of Science and Technology, Luoyang, Henan 471000, China)
摘要
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投稿时间:2023-09-23   网络发布日期:2024-07-20
中文摘要: 传统化疗方案治疗急性髓系白血病(AML)有一定疗效,但是复发/难治AML的治疗往往缓解率低、耐药性高、治疗效果欠佳,鉴于目前复发/难治AML的诊治现状,需要高效、耐受良好的治疗方案来改善患者的预后,以为AML的治疗提供新选择。本文针对维奈克拉联合阿扎胞苷及高三尖杉酯碱治疗复发/难治AML的疗效及机制做一综述。
Abstract:Traditional chemotherapy regimens have certain efficacy in the treatment of acute myeloid leukemia (AML), but the treatment of relapsed/refractory AML often results in low response rates, high resistance, and suboptimal therapeutic outcomes. Based on the current state of diagnosis and treatment for relapsed/refractory AML, there is a need for highly efficient and well-tolerated treatment regimens to improve the prognosis of AML patients and provide new choices for AML therapy. This article overviews the efficacy and mechanism of venetoclax in combination with azacitidine and homoharringtonine in the treatment of relapsed/refractory AML.
文章编号:     中图分类号:R733.71    文献标志码:A
基金项目:河南省医学科技攻关计划(联合共建)项目(LHJG20190547)
附件
引用文本:
程森,杨海平,赵小强,黄晖婷,辛静怡.维奈克拉联合阿扎胞苷及高三尖杉酯碱治疗复发/难治急性髓系白血病的疗效及机制[J].中国临床研究,2024,37(7):1120-1123.

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