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投稿时间：2023-08-28 网络发布日期：2024-07-20
投稿时间：2023-08-28 网络发布日期：2024-07-20
中文摘要: 目的 探讨2型糖尿病（T2DM）患者骨骼肌质量指数（SMI）与发生非创伤性肩袖损伤（RCT）的关系。
方法 回顾性分析2020年6月至2022年12月于晋中市第三人民医院内分泌及骨科住院的180例T2DM患者的临床资料，按照磁共振检查结果及病史分为T2DM合并非创伤性RCT组（T2DM+RCT 组,n=80）与T2DM未合并肩袖损伤组（T2DM+non-RCT 组，n=100）。比较两组患者一般资料、体脂率、骨骼肌质量、糖尿病病程、糖化血红蛋白（HbA1c）等的差异。使用二元logistic回归分析T2DM患者发生非创伤性RCT的危险因素。绘制受试者工作特征（ROC）曲线分析各因素对T2DM患者发生非创伤性RCT的预测价值。
结果 T2DM+RCT组女性患者比例、体重、身体质量指数（BMI）、糖尿病病程、体脂率及HbA1c水平均高于T2DM+non-RCT组（P＜0.05）； SMI低于T2DM+non-RCT组［6.10 (5.50,7.18) kg/m2vs 5.40 (4.50,6.10) kg/m2,Z=4.443,P<0.01］。二元logistic回归分析显示，SMI、BMI、糖尿病病程及HbA1c水平是RCT的影响因素（P＜0.05）。ROC曲线显示，SMI诊断T2DM患者合并RCT的最佳截断值为5.15 kg/m2，灵敏度为48.80%，特异度为82.00%，AUC=0.693（95%CI：0.614～0.771）。SMI、BMI、糖尿病病程及HbA1c四者联合诊断价值最高，灵敏度为81.30%，特异度为91.00%，AUC=0.926（95%CI：0.885～0.966）。
结论 T2DM患者非创伤性RCT的发生与SMI存在相关性，对非创伤性RCT形成有一定预测价值。
Abstract:Objective To investigate the relationship between skeletal muscle mass index (SMI) and non-traumatic rotator cuff tear(RCT) in patients with type 2 diabetes mellitus (T2DM).
Methods The clinical data of 180 T2DM patients who were hospitalized in the Department of Endocrinology and Orthopedics, the Third People's Hospital of Jinzhong from June 2020 to December 2022 were retrospectively analyzed. According to the results of MRI and medical history, the patients were divided into T2DM+RCT group (n=80) and T2DM+ non-RCT group (n=100). The general data, body fat ratio, skeletal muscle mass, duration of diabetes, glycosylated hemoglobin (HbA1c) and other factors were compared between the two groups. Binary logistic regression was used to analyze the risk factors for non-traumatic RCT in T2DM patients. The receiver operating characteristic (ROC) curve was used to analyze the predictive value of various factors for non-traumatic RCT in T2DM patients.
Results The proportion of female, body weight, body mass index(BMI), duration of diabetes, body fat ratio and HbA1c level in T2DM+RCT group were higher than those in T2DM+ non-RCT group (P< 0.05). The SMI was lower than that of the T2DM+ non-RCT group ［6.10 (5.50,7.18) kg/m2vs 5.40 (4.50,6.10) kg/m2,Z=4.443,P<0.01］. Binary logistic regression analysis showed that SMI, BMI, duration of diabetes and HbA1c were influencing factors for RCT. The ROC curve showed that the optimal cut-off value of SMI in diagnosing RCT in T2DM patients was 5.15 kg/m2, with a sensitivity of 48.80% and a specificity of 82.00%, and AUC=0.693 (95%CI: 0.614-0.771). The combination of SMI, BMI, duration of diabetes and HbA1c had the highest diagnostic value, with a sensitivity of 81.30% and a specificity of 91.00%, and AUC=0.926 (95%CI: 0.885-0.966).
Conclusion There is a correlation between SMI and non-traumatic RCT in diabetic patients, which has a particular predictive value for non-traumatic RCT.
keywords: Type 2 diabetes mellitus Skeletal muscle mass index Rotator cuff tear Non-traumatic rotator cuff tear Duration of diabetes
文章编号： 中图分类号：R685.4 文献标志码：A
基金项目:山西省回国留学人员科研资助基金（2023-095）；山西省自然科学基金面上项目（201901D111185）
| 作者 | 单位 |
| 张晓燕1 | 1. 山西医科大学基础医学院组胚教研室，山西 太原 030000； |
| 王丽花2 | 2. 晋中市第三人民医院，山西 晋中 030600； |
| 任美灵2 | 2. 晋中市第三人民医院，山西 晋中 030600； |
| 曹锡梅1，3 | 1. 山西医科大学基础医学院组胚教研室，山西 太原 030000； 3. 山西医科大学山西省临床级细胞治疗转化中试基地，山西 太原 030000 |
| Author Name | Affiliation |
| ZHANG Xiaoyan*, WANG Lihua, REN Meiling, CAO Ximei | *School of Basic Medical Sciences, Shanxi Medical University, Taiyuan, Shanxi 030000, China |
引用文本：
张晓燕,王丽花,任美灵,等.2型糖尿病患者骨骼肌质量指数与非创伤性肩袖损伤的相关性[J].中国临床研究,2024,37(7):1066-1069,1074.
张晓燕,王丽花,任美灵,等.2型糖尿病患者骨骼肌质量指数与非创伤性肩袖损伤的相关性[J].中国临床研究,2024,37(7):1066-1069,1074.