Abstract:Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection, and its pathogenesis is complex and has not been fully clarified at present. Its morbidity and mortality are still at a high level in countries around the world, but the changes of related indicators are related to the prognosis of sepsis. Neutrophil-to-lymphocyte ratio (NLR) may be associated with progression of inflammation, and elevated red blood cell distribution width (RDW) may be associated with inflammatory biomarkers and oxidative stress. Therefore, in order to clarify the correlation between RDW and NLR and the prognosis of patients with sepsis, this article reviews the existing research and progress, so as to provide a certain reference for evaluating the prognosis of patients with sepsis.