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投稿时间：2022-07-13 网络发布日期：2023-04-20
投稿时间：2022-07-13 网络发布日期：2023-04-20
中文摘要: 目的 评价体外膜肺氧合（ECMO）在成人暴发性心肌炎（FM）治疗中的安全性及有效性。方法 回顾性分析2015年11月至2021年12月在西安交通大学第一附属医院因重症FM接受静脉—动脉（V-A）ECMO治疗的成人患者22例的临床资料,包括临床表现、ECMO上机时机、置管方式、辅助时间以和治疗效果和预后。
〖HTH〗结果〖HTSS〗 共22例成人患者,男性8例,女性14例;年龄20~66岁;ECMO辅助的中位时间为96（74.3,131.4）h,ICU停留的中位时间为6.5（5.8,13.2）d。其中ECMO成功脱机且康复出院16例（72.7%）,2例（9.1%）家属放弃治疗,4例（18.2%）院内死亡。
结论 ECMO治疗FM患者是安全有效的。ECMO治疗期间需密切监测ECMO相关并发症。
中文关键词: 暴发性心肌炎 体外膜肺氧合 急性肺损伤；肾功能不全；临床预后
Abstract:Objective To evaluate the safety and effectiveness of extracorporeal membrane oxygenation（ECMO） in the treatment of fulminant myocarditis in adult patients.
Methods A retrospective analysis of 22 critically ill patients with fulminant myocarditis who received veno-arterial（V-A） ECMO therapy in the First Affiliated Hospital of Xi'an Jiaotong University during November 2015 and December 2021 was performed, which included clinical manifestation, the time of ECMO initiation, duration of ECMO, cannulation sites, treatment effect and prognosis.
Results There were 8 males and 14 females aged from 20 to 66 years. The median time assisted by ECMO was 96 (74.3131.4) hours, and the median stay time in ICU was 6.5 (5.8,13.2) days. Out of 22 patients, 16 patients were successfully weaned from ECMO and survived to discharge（72.7%）, 2 cases（9.1%） gave up treatment by family members and 4 patients（18.2%） died in hospital.
Conclusion In the treatment of patients with fulminant myocarditis,ECMO is safe and effective, however,the related complications should be closely monitored.
keywords: Fulminant myocarditis Extracorporeal membrane oxygenation Acute lung injury Renal in sufficiency Clinical outcomes
文章编号： 中图分类号：R452.2+1 R654.1 文献标志码：A
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引用文本：
郜扬, 陈强, 刘淼淼, 张颖, 邓超, 师桃, 郭锋伟.体外膜肺氧合治疗成人暴发性心肌炎的临床效果分析[J].中国临床研究,2023,36(4):542-546.
郜扬, 陈强, 刘淼淼, 张颖, 邓超, 师桃, 郭锋伟.体外膜肺氧合治疗成人暴发性心肌炎的临床效果分析[J].中国临床研究,2023,36(4):542-546.