Abstract:Objective To investigate the effect of enhanced recovery after surgery (ERAS) in the perioperative management of gynecological malignant tumor patients. Methods Eight databases including PubMed, EMBASE, Web of Science, Cochrane Library, CNKI, Wanfang, VIP and CBM were searched. The clinical trials comparing the effect of ERAS concept and traditional concept in the perioperative period of gynecological malignant tumor patients from the establishment of the database to October 2021 were retrieved, including randomized controlled trails (RCT), cohort studies and case-control studies. Cochrane risk bias tool and Newcastle Ottawa scale were used to evaluate the literature quality of RCT and non-RCT respectively. Revman 5.4 was selected for Meta-analysis. Results There were 28 studies included eventually, with a total of 3 901 patients. Among them, there were 1 897 cases in the experimental group and 2 004 cases in the control group. Meta-analysis showed that there were significant differences between ERAS group and traditional group in the operation time, the time of the first postoperative exhaust and defecation, getting out of bed and eating, the postoperative hospital stay, and the incidence of postoperative complications (P<0.01). Conclusion Compared with the traditional concept, the perioperative application of ERAS concept in gynecological malignant tumor patients can shorten the operation time, the time of the first postoperative exhaust and defecation, getting out of bed and eating, and the postoperative hospital stay, and reduce the incidence of postoperative complications, which is a safe and feasible measure.