Abstract:Objective To study the epidemiological characteristics and drug resistance of pathogens in children pneumonia in Haikou area. Methods From April 2019 to October 2021, 427 children with pneumonia treated in the Second Affiliated Hospital of Hainan Medical University were selected, all children were tested for pathogenic bacteria and drug sensitivity, and the epidemiological characteristics of children's pneumonia were analyzed. Results Among the 427 children with pneumonia, the proportion of 3-5 years old was relatively high, and the proportions of male and female, the proportions in spring, summer, autumn and winter were similar. A total of 166 pathogenic bacteria were detected in 427 children with pneumonia, with a detection rate of 38.88%. A total of 257 strains of pathogenic bacteria were detected in 166 children with pathogenic bacteria, of which gram-negative bacteria were higher than gram-positive bacteria. Gram negative bacteria were mainly Klebsiella pneumoniae, followed by Acinetobacter baumannii and Escherichia coli respectively. Staphylococcus aureus and Streptococcus pneumoniae were the main gram positive bacteria. Klebsiella pneumoniae has the highest resistance rate to compound sulfamethoxazole, Acinetobacter baumannii has the highest resistance rate to gentamicin, Escherichia coli has the highest resistance rate to ampicillin, Staphylococcus aureus has the higher resistance rate to penicillin and erythromycin, Streptococcus pneumoniae has the higher resistance rate to compound sulfamethoxazole, tetracycline, erythromycin, and clindamycin. Conclusions Pathogenic bacteria of children pneumonia in Haikou area are mostly gram negative bacteria, and the drug resistance of different pathogenic bacteria is also different. Clinical detection of drug-resistant pathogenic bacteria should be strengthened.