Abstract:Objective Based on the construction of stroke center, to explore how to build an acute stroke treatment system according to local conditions, and observe the clinical effect of the construction of stroke treatment system on the improvement of treatment efficiency of ischemic stroke. Methods The patients with acute ischemic stroke treated before the establishment of the stroke center of Zhaoqing First People's Hospital (January 1, 2017 to December 31, 2017) were collected retrospectively as the control group (n=1 029), and patients with acute ischemic stroke after the establishment of the stroke center (September 1, 2018 to August 31, 2019) were collected as the observation group (n=1 720). The improvement of management performance indicators, clinical treatment performance indicators, complication prevention performance indicators, secondary prevention performance indicators, rehabilitation treatment performance indicators and health economics indicators of the green channel of acute ischemic stroke were compared between the two groups. Results Through multidisciplinary cooperation in the construction of stroke treatment system, the admission intravenous thrombolysis time (DNT) of acute ischemic stroke was shortened from 120 min to 82 min before the establishment of stroke treatment system, and the proportion of intravenous thrombolysis and average hospitalization cost were significantly higher than those before the construction of the system (P<0.05). The incidence of aspiration pneumonia, in-hospital mortality of stroke and the proportion of bone flap decompression decreased. There was significant difference between the two groups (P<0.05, P<0.01). There was no significant difference between the two groups in the proportion of intravascular treatment, the incidence of lower extremity deep venous thrombosis (DVT), the use of antiplatelet drugs within 48 hours of admission and after discharge, the incidence of gastrointestinal bleeding, the proportion of rehabilitation treatment, the screening rate of swallowing dysfunction and the length of hospital stay (P>0.05). Conclusion The establishment of an organized stroke treatment system can significantly shorten the treatment time of patients with acute ischemic stroke, improve the prognosis of patients and reduce the incidence of complications.