Abstract:Objective To explore the application value of 3D-Slicer software in evacuation of hypertensive intracerebral hematomas in basal ganglia region. Methods A total of 178 patients with hypertensive intracerebral hemorrhage in basal ganglia region in the Handan Cetral Hospital from September 2018 to September 2019 were randomly divided into observation group (n=86) and control group (n=92).Before minimally invasive puncture and drainage was conducted in both groups,3D-Slicer assisted localization was used in observation group,and localization with CT guidance was used in control group.The accuracy of puncture site,hematoma clearance rate,extubation time,operation time,postoperative complications and prognosis were compared between two groups. Results The accuracy rate of puncture site and hematoma clearance rate of 3 days after operation in observation group were significantly higher than those in control group,and the operation time and the time of extubation were shorter than those in control group (all P<0.01).The total incidence of complications in observation group was significantly lower than that in control group (8.14% vs 27.17%,χ2=10.921,P<0.01).At three months after operation,National Institutes of Health Stroke Scale(NIHSS) were lower than those before operation in two groups and was significantly lower in observation group than that in control group (P<0.01).Activities of daily living(ADL)grading in observation group was superior to that in control group(P<0.01). Conclusion 3D-Slicer assisted localization can provide more accurate puncture position for hypertensive intracerebral hemorrhage in basal ganglia region and can improve hematoma clearance rate and prognosis of the patients.