Abstract:Objective To observe the therapeutic effect of Chaihu Danggui powder on ascites due to hepatitis B cirrhosis with Shaoyang-Taiyin disease and symptoms to provide clinical basis for the treatment of ascites caused by hepatitis B cirrhosis. Methods A total of 113 patients with ascites due to hepatitis B cirrhosis with Shaoyang-Taiyin disease and symptoms treated from September 2018 to December 2019 were selected and divided into treatment group (n=57) and control group (n=56) according to the random number table method.The routine conventional therapy was given in control group,and Chaihu Danggui powder was given on the basis of routine conventional treatment in treatment group.The comprehensive effects (including on edema,abdominal circumference,24h urine volume,weight),abdominal distension relief time,Traditional Chinese medicine(TCM) syndrome and SF-36 quality of life questionnaire (SF-36) were observed and compared between two groups. Results After treatment,the total effective rate in treatment group was significantly higher than that in control group (96.49% vs 80.36%,P＜0.01).TCM syndrome score and SF-36 score were significantly improved compared with those before treatment in two groups (all P<0.05),and TCM syndrome score,SF-36 score and abdominal distension relief time in treatment group were better than those in control group (P<0.05，P<0.01). Conclusion In the treatment of ascites due to hepatitis B cirrhosis with Shaoyang-Taiyin disease and symptoms,Chaihu Danggui powder is effective with less adverse reactions and high safety.