Abstract:Objective To investigate the clinic pathological features and survival of gastric adenocarcinoma. Methods A total of 85 patients with gastric adenocarcinoma who received treatment from January 2007 to August 2012 were selected, and their clinic pathological features were collected. All the patients were followed up for 5 years to record their survival situation. Results There were 59 males and 26 females in all the 85 patients with gastric adenocarcinoma (age 56.5±3.1). There were 20 patients (23.53%) in stage Ⅱ, 58 patients (68.24%) in stage Ⅲ and 7 patients (8.24%) in stage Ⅳ. There were 58 patients with lymph node metastasis (68.24%) and 27 patients without lymph node metastasis (31.76%). Abdominal pain and diarrhea were the main clinical symptoms (65.88%), followed by fever, fatigue and acid regurgitation, accounting for 31.76% and 22.35% respectively. The results of single factor analysis showed that TNM staging (χ²=4.157, P=0.042), the maximum diameter of tumor (χ²=4.876, P=0.032) affected the prognosis of the patients. The results of multifactor analysis showed that the tumor′s maximum diameter >5 cm (OR=2.249, 95%CI:1.312-3.243, P=0.004), TNM staging Ⅳ (OR=3.211, 95%CI:1.243-4.322, P=0.016) and lymph node metastasis (OR=3.372, 95%CI:1.445-3.981, P=0.032) were independent risk factors affecting the prognosis of the patients. Conclusion The primary gastric adenocarcinoma has a bad prognosis. Surgical treatment should be performed in time. The maximum diameter of tumor and TNM staging are the key to the prognosis of primary gastric adenocarcinoma.