Abstract:Objective To compare the efficacy of pericapsular nerve group block （PENGB） and fascia iliaca compartment block（FICB）in pain management from hip fractures. Methods Patients with hip fracture who needed surgery in the Affiliated Dongnan Hospital of Xiamen University from January 2018 to December 2021 were prospectively selected and randomly divided into three groups：30 patients received PENGB（PENGB group），22 patients received FICB（FICB group）and 20 patients did not receive any nerve block（blank group）. The visual analog scale（VAS）scores，intraoperative fentanyl dosage，time of first use of the analgesic pump postoperatively，and total morphine dosage within 24 hours postoperatively were compared among the three groups. Results There was no statistically significant difference in VAS scores among the three groups before the block，in the anesthesia recovery room，at 6 h and 12 h postoperatively（P＜0.05）. Compared with the FICB group and the blank group，the time of first use of the analgesic pump postoperatively in the PENGB group was significantly prolonged（P<0.05）. The total dosage of morphine within24 h after surgery and fentanyl after surgery decreased in the order of blank group，FICB group and PENGB group［（64.50±12.44）mg，（54.77±18.42）mg，（50.76±15.36）mg，F=4.692，P=0.012；（134.75±45.41）μg，（102.10±40.11）μg，（99.09±31.61）μg，F=5.819，P=0.005］。There was no statistically significant difference in the maximum flexion angle of hip joint among the three groups at 6 h，24 h and 48 h after surgery（P > 0.05）. The incidence of anesthesia?related complications and intraoperative blood loss showed no significant differences among the groups（P＜0.05）. Conclusion PENGB has a good analgesic effect on hip fracture，which can reduce the dosage of fentanyl during surgery and morphine after surgery.