Abstract:Balanced thinking is the core theory of Chinese medicine, which runs through the whole process of disease differentiation and treatment in Chinese medicine. Professor Wu Chengyu has been engaged in Chinese medicine clinical practice for more than 50 years, and has rich experience in differentiating and treating malignant tumors, thus forming here own unique academic thoughts: she believes that the imbalance between yin and yang is closely related to the development and progression of malignant tumors. In clinical practice, the internal environment of the body is balanced by flexibly using drug bias such as attack and tonify balance, cold and heat balance, ascending and descending balance, moisturizing and dryness balance, and from the perspective of dynamic balance of prescription compatibility, so as to reduce the pain of patients and prolong the life of patients. This paper summarizes Professor Wu Chengyu's experience in treating malignant tumors with balanced thinking, in hope to provide references for scholars.