Abstract:Objective To summarize the clinical experience of multiple incision contradrainage and necrotic fascia resection in the treatment of severe necrotizing fasciitis of thoracic and abdominal wall. Methods The clinical data of 3 patients with necrotizing fasciitis of thoracic and abdominal wall admitted to Xi'an Aerospace General Hospital from November 2019 to March 2021 were retrospectively analyzed. All 3 patients received multiple incisions contradrainage and necrotic fascia resection, with 1 patient combined with scrotal and testicular resection. The prognosis, laboratory tests and bacterial culture results of patients were analyzed. Results There were 2 males and 1 female. In 3 patients, C-reactive protein was higher than 150 mg/L, procalcitonin was higher than 5ng /mL, and white blood cells were not significantly elevated and even decreased. All patients were treated with surgery, anti-infection and comprehensive treatment. The hospitalization time of the three patients was 36, 7 and 48 days respectively. One patient gave up treatment and died. The other 2 patients obtained a better prognosis and quality of life. Conclusion Early diagnosis, early operation, reasonable selection of surgical methods, standard anti-infective therapy and life support can effectively improve the survival rate, better prognosis and life quality of patients with necrotizing fasciitis.