本文已被:浏览 15次 下载 3次
Received:February 04, 2024 Published Online:December 21, 2024
Received:February 04, 2024 Published Online:December 21, 2024
中文摘要: 目的 探讨光学相关断层扫描血管成像术(OCTA)评估成年近视患者的黄斑区视网膜血流密度、视网膜厚度(RT)及其与年龄、近视程度的关系。方法 选取2021年2月至2023年2月空军军医大学第一附属医院眼科门诊就诊的100例(195眼)成年近视患者,按等效球镜度的不同将患者分为低度近视组(-3.00~-0.50 D,33例65眼)、中度近视组(-6.00~<-3.00 D,33例65眼)和高度近视组(<-6.00 D,34例65眼)。所有患者接受准分子激光手术治疗,行OCTA检查并量化黄斑区视网膜浅层血流密度、RT,比较三组黄斑区视网膜血流密度及RT的差异,并采用Pearson相关性分析其与年龄、近视程度的相关性;比较手术前及术后6个月的手术相关指标。结果 低高度近视组黄斑内环区、外环区的血管长度密度(VLD)、血管灌注密度(VPD)及RT比较差异有统计学意义(P<0.05)。Pearson相关性分析结果显示,黄斑区中心凹VLD、VPD、RT与等效球镜度、年龄、眼轴长度无相关性(P>0.05);黄斑内环、外环区的VLD、VPD、RT与等效球镜度呈正相关,与眼轴长度呈负相关,且VLD、VPD与年龄呈负相关(P<0.05)。结论 成年近视患者的黄斑区视网膜血流密度、RT随着近视程度、年龄的增加而减少。
Abstract:Objective To evaluate the macular retinal blood flow density and retinal thickness(RT) in adult myopia patients by optical correlation tomography angiography (OCTA) and their relationship with age and myopia. Methods A total of 100 adult myopic patients (195 eyes) who visited the ophthalmology outpatient department of the First Affiliated Hospital of Air Force Medical University from February 2021 to February 2023 were selected. The patients were divided into low myopia group (-3.00 to -0.50 D, 33 cases with 65 eyes), moderate myopia group (-6.00 to <-3.00 D, 33 cases with 65 eyes) and high myopia group (<-6.00 D, 34 cases with 65 eyes).All patients underwent photorefractive keratectomy and OCTA examination to quantify macular retinal superficial blood flow density and RT. Differences in macular retinal blood flow density and RT among the three groups were compared, and Pearson correlation analysis was conducted to assess their relationship with age and degree of myopia. Surgical-related indicators before and 6 months after surgery were compared. Results There were significant differences in vascular length density (VLD), vascular perfusion density (VPD) and RT in the inner and outer macular regions among the low, moderate, and high myopia groups (P<0.05). Pearson correlation analysis showed no correlation between central foveal VLD, VPD, RT, equivalent spherical degree, age, and axial length (P>0.05). VLD, VPD, and RT in the inner and outer macular regions were positively correlated with equivalent spherical degree and negatively correlated with axial length, with VLD and VPD negatively correlated with age (P<0.05). Conclusion The macular retinal blood flow density and RT decrease with increasing myopia and age in adult myopic patient.
文章编号: 中图分类号:R778.1 文献标志码:A
基金项目:
Author Name | Affiliation |
ZHU Jinting, FENG Jie | Department of Ophthalmology, the First Affiliated Hospital of Air Force Medical University, Xi’an,Shaanxi 710000, China |
Author Name | Affiliation |
ZHU Jinting, FENG Jie | Department of Ophthalmology, the First Affiliated Hospital of Air Force Medical University, Xi’an,Shaanxi 710000, China |
引用文本: