Abstract:ObjectiveTo investigate the therapeutic efficacy of Huiyang Decoction on traumatic hemorrhagic shock and to propose a new viable treatment approach for the disease. Methods A retrospective analysis was performed on a cohort of 40 patients with traumatic injuries who underwent surgical intervention at the Department of Critical Care Medicine, Wuxi Ninth Peoples Hospital Affiliated to Soochow University, from March 2022 to December 2023. A total of 20 patients who received standard hemorrhagic shock treatment and received postoperative blood transfusion to hemoglobin 80 g/L were selected as the control group. A total of 20 patients who were treated with Huiyang decoction for 3 days on the basis of the above treatment were selected as the observation group.The improvement of serum creatine kinase (CK) and creatine kinase isoenzyme (CK-MB) in the two groups was observed. The total effective rate was defined as the recovery + significant improvement + improvement of CK and CK-MB to compare the total effective rate after treatment, and TCM symptom score before and after treatment between two groups. Results After 3-day treatment, the CK level in the observation group was higher than that in the control group before treatment (P＜0.05), and decreased after treatment, but there was no significant difference compared with the control group (P＞0.05). CK-MB levels showed no significant difference between the two groups before treatment (P＞0.05), and that in the observation group was lower compared with the control group after treatment (P＜0.01). The total effective rate of CK-MB in the observation group was significantly higher than that in the control group(85.00% vs 55.00%, χ²=4.290， P＜0.05). The observation group slightly surpassed control group in the total effective rate of CK，however, there was no statistically significant difference (50.00% vs 30.00%, χ²=1.670, P＞0.05). Following treatment, both groups exhibited a significant reduction in TCM syndrome scores for dizziness, fatigue, and cold limbs compared to pre-treatment(P＜0.01), and the observation group demonstrated lower TCM syndrome scores compared to the control group (P＜0.05). Conclusion Huiyang Decoction has a beneficial effect on traumatic hemorrhagic shock, and can increase TCM symptom scores and improve abnormalities of serum CK-MB level after hemorrhagic shock.