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中国临床研究英文版:2024,37(8):1160-1163,1171
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艾司氯胺酮联合其他麻醉药物的临床应用进展
(1. 广东医科大学,广东 湛江 524000;2. 广东医科大学肇庆市第一人民医院,广东 肇庆 526000)
Progress in clinical application of esketamine combined with other anesthetic drugs
摘要
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Received:March 11, 2024   Published Online:August 20, 2024
中文摘要: 艾司氯胺酮是一种N-甲基-D-天冬氨酸(NMDA)受体拮抗剂,较氯胺酮的麻醉镇痛效果更好。艾司氯胺酮可作用于神经系统、呼吸系统、循环系统等,因其起效较快、代谢迅速,在麻醉管理中具有独特的优势。艾司氯胺酮不仅可单独应用于短效麻醉操作中,还可与多种麻醉药物联合应用,为各类临床手术及门诊检查的麻醉管理提供了新的选择。
中文关键词: 艾司氯胺酮  氯胺酮  麻醉  丙泊酚  咪达唑仑  镇痛
Abstract:Esketamine is an N-methyl-D-aspartic acid (NMDA) receptor antagonist, which has a better effect than ketamine in anesthesia. Esketamine can act on the nervous system, respiratory system, circulatory system, etc. Due to its fast onset and rapid metabolism, it has unique advantages in anesthesia management. Esketamine can not only be used alone in short-term anesthesia operations, but also in combination with various anesthetic drugs, providing a new choice for anesthesia management in various clinical surgeries and outpatient examinations.
文章编号:     中图分类号:R971+.2    文献标志码:A
基金项目:国家卫健委科学技术研究所课题(2021KYSHX01503)
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