本文已被:浏览 109次 下载 149次
Received:August 24, 2023 Published Online:July 20, 2024
Received:August 24, 2023 Published Online:July 20, 2024
中文摘要: 目的 探讨能量计算机断层血管造影(CTA)斑点征与高血压脑出血(HICH)患者血肿扩大风险的相关性。
方法 纳入2019年1月至2022年9月泸州市人民医院收治的115例HICH患者,所有患者均接受脑出血常规治疗,住院期间根据是否发生血肿扩大情况将所有的研究对象分为扩大组和未扩大组。分析两组患者人口学资料、临床特征资料,实验室检查资料等,采用多因素logistic分析影响血肿扩大的相关因素。
结果 115例HICH患者中41例患者出现血肿扩大为扩大组,74例未出现血肿扩大为未扩大组。单变量分析显示两组患者一般资料组间对比差异无统计学意义(P>0.05);扩大组CTA斑点征得分高于未扩大组,斑点征出现在混合动脉和延迟融合期以及不规则血肿形态占比高于未扩大组、首次CT时的血肿体积大于未扩大组(P<0.05);多因素logistic回归分析显示,斑点征得分(OR=23.703, 95%CI:1.336~420.556)、血肿体积(OR=1.618, 95%CI:1.090~2.399)、斑点征出现在混合动脉期(OR=2.198, 95%CI:1.164~4.152)和延迟融合期(OR=2.553, 95%CI:1.363~4.781)是血肿扩大发生的独立影响因素(P<0.05)。
结论 首次CT时的血肿体积、CTA斑点征得分、斑点征出现于混合动脉以及延迟融合期是HICH患者发生血肿扩大的影响因素。
中文关键词: 能量计算机断层血管造影 高血压 脑出血 血肿扩大 斑点征
Abstract:Objective To investigate the correlation between spot sign (SS) on energy computed tomography angiography (CTA) and the risk of hematoma enlargement (HE) in patients with hypertensive intracerebral hemorrhage (HICH).
Methods A total of 115 patients with HICH admitted to Luzhou People's Hospital from January 2019 to September 2022 were included. All patients received conventional treatment for intracerebral hemorrhage, and during hospitalization, they were divided into enlarged group and non-enlarged group according to whether HE occurred. Demographic data, clinical characteristics, and laboratory examination data were analyzed, and multivariate logistic regression analysis was used to identify the factors associated with HE.
Results Among the 115 patients with HICH, 41 had HE as the enlarged group, while 74 did not have HE as the non-enlarged group. Univariate analysis showed that there was no significant difference in general information between the two groups (P>0.05); CTA SS score was higher in the enlarged group than that in the non-enlarged group, and the proportion of SS occurring in mixed arterial phase and delayed fusion phase, as well as irregular hematoma shape, was higher than those in the non-enlarged group. The volume of hematoma on initial CT was larger in the enlarged group than that in the non-enlarged group (P<0.05). Multivariate logistic regression analysis showed that SS score (OR=23.703, 95%CI: 1.336-420.556), hematoma volume (OR=1.618, 95%CI: 1.090-2.399), occurrence of SS in mixed arterial phase (OR=2.198, 95%CI: 1.164-4.152), and delayed fusion phase (OR=2.553, 95%CI: 1.363-4.781) were independent risk factors for HE (P<0.05).
Conclusion The volume of hematoma on initial CT, CTA SS score, and occurrence of SS in mixed arterial phase and delayed fusion phase are related to the occurrence of HE in patients with HICH.
keywords: Energy computed tomography angiography Hypertension Cerebral hemorrhage Hematoma enlargement Spot sign
文章编号: 中图分类号:R743.34 文献标志码:A
基金项目:四川省医学(青年创新)科研课题(Q19032)
引用文本: