Abstract:Secondary hyperparathyroidism (SHPT), as a common complication of chronic renal failure, has always been a focus of clinical research on the treatment of parathyroidism. The pathogenesis of SHPT is due to the abnormal secretion of parathyroid hormone caused by changes in the internal environment of the human body after the progression of chronic kidney disease to the end stage, resulting in the secretion and metabolic disorders of calcium and phosphorus plasma, leading to serious complications of functional disorders in various systems including the urinary system, skeletal system, cardiovascular system, and even the whole body. This article reviews the current status of surgical treatment of SHPT in patients with chronic kidney disease at home and abroad, in order to increase surgeons' understanding of surgical treatment, so as to provide patients with better surgical treatment program guidance and improve the quality of life of patients with SHPT.