Abstract:Endometrial carcinoma (EC) is one of the most common gynecological malignancies in women. In recent years, the incidence and mortality rates of EC have been steadily increasing, and the trend is towards a younger age at onset. Early diagnosis of EC can improve long-term prognosis for patients, but consensus on early detection methods for EC has not yet been reached. This article reviews the advantages and disadvantages of early intrauterine detection methods such as endometrial tissue biopsy, endometrial uterine sampling devices, hysteroscopy, and uterine lavage fluid, as well as early extrauterine detection methods such as imaging, peripheral blood related indicators, and DNA methylation.