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Received:March 18, 2024 Published Online:May 20, 2024
Received:March 18, 2024 Published Online:May 20, 2024
中文摘要: 甲基化修饰作为表观遗传学的研究热点，通过调节基因的表达，在细胞信号转导和组织特异性分化等方面发挥着重要作用。在椎间盘的退变与修复过程中，甲基化修饰扮演着重要角色。本文综述了甲基化修饰在椎间盘退变发病机制中的作用及特点，并对其未来发展前景进行展望。
Abstract:Methylation modification is a hot research topic in epigenetics. It plays an important role in cell signal transduction and tissue-specific differentiation by regulating gene expression. Methylation modification also plays a significant role in intervertebral disc degeneration and repair. This article reviews the role and characteristics of methylation modification in the pathogenesis of intervertebral disc degeneration and provides an outlook for future development.
文章编号： 中图分类号：R681.53 文献标志码：A
基金项目:江苏省自然科学基金面上项目（BK20201130）
| Author Name | Affiliation |
| HAN Tong, TIAN Jiwei | BenQ Medical Center, The Affililated BenQ Hospital of Nanjing Medical University, Nanjing, Jiangsu 210000, China |
| Author Name | Affiliation |
| HAN Tong, TIAN Jiwei | BenQ Medical Center, The Affililated BenQ Hospital of Nanjing Medical University, Nanjing, Jiangsu 210000, China |
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