Abstract:Objective To explore the nursing value of standardized process intervention on patients receiving extracorporeal membrane oxygenation (ECMO) support for cardiopulmonary failure after off-pump coronary artery bypass (OPCAB). Methods A total of 90 patients with cardiopulmonary failure after OPCAB receiving ECMO support in the First Affiliated Hospital of Xinjiang Medical University from May 2019 to December 2022 were selected as observation subjects, and were divided into observation group and control group by stratified randomization method, with 45 cases in each group. The control group was given routine nursing intervention, and the observation group was given standardized process intervention. The clinical indicators (ICU stay, ICU cost, ECMO auxiliary time, hospital stay) and cardiac function (European system for cardiac operative risk evaluation, EuroScore) score and respiratory status (dyspnoea, eosinopenia, consolidation, acidemia and atrial fibrillation, DECAF) score before and 1 month after intervention were compared between two groups. Complications and survival rate were recorded in both groups. Results The ICU stay, hospital stay and ICU cost were significantly less than those in control group (P＜0.05). One month after the intervention, the scores of EuroScore and DECAF in both groups were significantly decreased, and the scores in observation group were significantly lower than those in control group (P＜0.05). The total incidences of complication was significantly lower in observation group than that in control group (P=0.035), but there was no statistical difference in survival between the two groups(P＞0.05). Conclusion The application of standardized process intervention for patients with cardiopulmonary failure after OPCAB undergoing ECMO support can effectively shorten the ICU stay and hospital stay, and reduce the incidences of complications.