Abstract:Objective To explore the effect of preoperative information support strategies on salivary cortisol levels in patients with breast cancer. Methods From March 2022 to February 2023, 72 female patients with breast cancer who were hospitalized in Breast Surgery Department and planned to receive surgical treatment were selected. According to the random number table method, 36 patients were divided into the control group, who received routine preoperative disease education, and 36 patients in the observation group, who received the trinity preoperative information support strategy of “outpatient-ward-hand operating room” on the basis of routine education. Measure the salivary cortisol level of patients before and after intervention, and evaluate the patient's anxiety level using the Self-rating Anxiety Scale (SAS). Results Before the intervention, there was no statistically significant difference in salivary cortisol levels and SAS scores between the two groups of patients (P＞0.05). After the intervention, the salivary cortisol levels and SAS scores of the observation group were significantly lower than those of the control group (P＜0.05), and significantly decreased compared to before the intervention (P＜0.05). Conclusion The “outpatient-ward-operating room” trinity preoperative information support strategy ensures that patients receive attention and needed information support, which can effectively reduce the salivary cortisol level of breast cancer patients and alleviate preoperative anxiety.