Abstract:Objective To explore the application effect of structured follow-up based on patient-reported outcome (PRO) in patients undergoing endoscopic submucosal dissection (ESD) for early gastric cancer. Methods A total of 198 patients with early gastric cancer treated by ESD in the Department of Gastroenterology, Drum Tower Hospital Affiliated to Medical School of Nanjing University from January 2022 to December 2022 were selected as the research subjects. Patients admitted before June 2022 were included in the control group and received routine follow-up, while those admitted after June 2022 were included in the experimental group and received structured follow-up based on PRO. The PRO situation, endoscopic reexamination rate within half a year after surgery, Hp eradication rate, patient satisfaction, and attitudes of medical staff towards patient report outcome in the experimental group were compared and analyzed.Results The completion rates of the health habits formation report form (74.07% vs 19.66%), endoscopy follow-up report form (61.73% vs 29.91%), and Hp eradication therapy report form (72.72% vs 24.14%) were superior in the observation group compared to the control group (P＜0.05). The observation group had a higher rate of on-time endoscopic follow-up within six months compared to the control group (69.14% vs 45.30%, P＜0.05), and the compliance of Hp-positive patients with Hp eradication therapy was higher than that of the control group (81.82% vs 27.59%, P＜0.05). Patient satisfaction in the observation group was higher than that in the control group (P＜0.05). The healthcare personnel in the observation group exhibited a relatively high level of PRO attitude. Conclusion Structured follow-up based on PRO can effectively enhance PRO, endoscopy follow-up rates, Hp eradication rates, and patient satisfaction in patients after early gastric cancer ESD, receiving support from the majority of healthcare personnel.