Abstract:Objective To investigate the intervention effect of personalized swallowing rehabilitation in patients with oral cancer after free flap transplantation (OC-FFT). Methods From January to December 2022, 88 patients who received OC-FFT in Nanjing Stomatology Hospital were selected as the research objects. And they were divided into control group and intervention group randomly (n=44, each). The routine nursing intervention was conducted in control group, while personalized swallowing rehabilitation combined with routine nursing intervention was conducted in intervention group (twice a day, continued for 10 days). Mann Assessment of Swallowing Ability-Oral Cancer (MASA-OC), percentage of weight loss, nutritional indicators (prealbumin, albumin, hemoglobin), gastric tube removal time, and quality of life scale (University of Washington Quality of Life Questionnaire version 4, UW-QOLv4) were used to evaluate the intervention effect. Results Compared with patients in the control group, the MASA-OC score and percentage of body weight loss at 7 days, 14 days, and 1 month after operation were better than those in the control group (P＜0.05). And postoperatively, the nutritional indicators, gastric tube removal time, and quality of life of the intervention group were better than those of the control group (P＜0.05). Conclusion Personalized swallowing rehabilitation can improve the swallowing function of patients with OC-FFT, help patients remove nasogastric tube as soon as possible to resume oral feeding, and improve their nutritional status and quality of life.