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Received:February 02, 2023 Published Online:November 20, 2023
Received:February 02, 2023 Published Online:November 20, 2023
中文摘要: 目的 分析彩色多普勒超声(CDU)在甲状腺恶性结节患者中的超声特征及其诊断效能,为临床诊断和鉴别诊断提供参考。方法 回顾性分析2020年1月至2022年1月陕西省中医医院110例甲状腺结节患者的临床资料,根据病理检查结果分为良性组和恶性组,比较两组超声特征、血流分型及血流参数。结果 110例甲状腺结节患者中恶性26例,良性84例。CDU检查诊断恶性甲状腺结节的敏感性、特异性以及准确度分别为88.46%、95.24%、93.64%。恶性组形态不规则(76.92% vs 10.71%, χ2=44.833)、低回声、纵横比≥1(69.23% vs 10.71%,χ2=36.708)患者占比,及血流分型Ⅲ、Ⅳ型占比高于良性组(P<0.05)。恶性组收缩期峰值血流速度(PSV)、阻力指数(RI)高于良性组,舒张末期血流速度(EDV)低于良性组(P<0.05)。结论 CDU检查在甲状腺结节良恶性的鉴别中具有良好的诊断效能,其中形态不规则、低回声、纵横比≥1是恶性甲状腺结节的超声特征,其主要血流分型为Ⅲ、Ⅳ型,具有较高的RI、PSV。
Abstract:Objective To analyze the ultrasonographic features and diagnostic efficacy of color Doppler ultrasonography (CDU) of malignant thyroid nodules, to provide reference for clinical diagnosis and differential diagnosis. Methods The clinical data of 110 patients with thyroid nodules treated in Shaanxi Provincial Hospital of Chinese Medicine from January 2020 to January 2022 were retrospectively collected, and were divided into the benign group and the malignant group according to the pathological examination. The ultrasonic features, blood flow classification and blood flow parameters of the two groups were compared. Results Among the 110 patients with thyroid nodules, 26 were malignant and 84 were benign. The sensitivity, specificity and accuracy of CDU in the diagnosis of malignant thyroid nodules were 88.46%, 95.24% and 93.64%, respectively. The proportion of patients with irregular morphology (76.92% vs 10.71%, χ2=44.833), low echo, aspect ratio ≥1 (69.23% vs 10.71%, χ2=36.708), blood flow types Ⅲ and Ⅳ were higher than those in the benign group (P<0.05). Peak systolic blood flow velocity (PSV) and resistance index (RI) in the malignant group were higher than those in the benign group, and end diastolic velocity (EDV) was lower than that in the benign group (P<0.05). Conclusion CDU examination has good diagnostic efficacy in the differentiation of benign and malignant thyroid nodules. Irregular morphology, low echo, and aspect ratio ≥ 1 are the ultrasound features of malignant thyroid nodules. The main blood flow types are Ⅲ and Ⅳ, with higher RI and PSV.
keywords: Thyroid nodules, benign and malignant Color Doppler ultrasound Thyroid cancer Resistance index End diastolic velocity Peak systolic blood flow velocity
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基金项目:国家卫生健康委“十四五”规划全国重点课题(YYWS4188)
Author Name | Affiliation |
XU Hua, MA Zhe | Ultrasound Room, Shaanxi Provincial Hospital of Chinese Medicine, Xian, Shaanxi 710003, China |
Author Name | Affiliation |
XU Hua, MA Zhe | Ultrasound Room, Shaanxi Provincial Hospital of Chinese Medicine, Xian, Shaanxi 710003, China |
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