Abstract:Atherosclerosis (AS) has a high incidence rate in middle-aged and elderly patients, and the pathogenesis of AS has not been fully clarified so far. The risk factors of AS include hypertension, diabetes, hyperlipidemia, smoking, genetic factors, etc. In addition, environmental factors also play a decisive role in the occurrence and development of AS. In recent years, some studies have shown that intestinal microorganisms can participate in the occurrence and development of AS by regulating a series of processes of endocrine and body metabolism. This paper briefly summarizes the current understanding of the relationship between intestinal flora and the occurrence and development of AS, in order to provide a new idea for the diagnosis and prevention of AS.