本文已被:浏览 482次 下载 277次
Received:September 30, 2022 Published Online:August 20, 2023
Received:September 30, 2022 Published Online:August 20, 2023
中文摘要: 目的探讨口服乳果糖在结肠镜诊疗前肠道准备中的效果及患者接受度。方法选取在2021年5月至2022年5月南京市中医院内镜中心拟行结肠镜检查及治疗的560例患者为研究对象,随机分为观察组(n=289)和对照组(n=271),分别口服乳果糖加饮用水1500mL和复方聚乙二醇电解质加饮用水4000mL,均分次口服;记录两组患者基本资料、肠道清洁程度、用药方案的接受度、泡沫情况、病变及不良反应。结果两组肠镜检查时波士顿评分、气泡评分、结直肠息肉检出率差异无统计学意义(P>0.05)。观察组患者对肠道准备用药方案的接受度高于对照组(P<0.05),恶心呕吐症状评分低于对照组(P<0.05),口干、乏力的发生率高于对照组(28.37%vs3.69%, χ2=7.862,P<0.05;10.73%vs3.32%, χ2=3.275,P<0.05)。腹胀、腹痛、头晕头痛等差异无统计学意义(P>0.05)。结论渗透性泻剂乳果糖在结肠镜诊疗前肠道准备中实施疗效确切且不良反应少,结肠道清洁效果较好,利于结直肠病变的检出,患者的接受度好。
Abstract:ObjectiveTo observe the effect and the patient acceptance of oral lactulose in bowel preparation before colonoscopy diagnosis and treatment. MethodsA total of 560 patients, who were scheduled to undergo colonoscopy for diagnosis and treatment in Anorectal Center of Nanjing Hospital of TCM from May 2021 to May 2022 were selected as research subjects and were randomly divided into observation group(n=289) and control group(n=271). Lactulose plus drinking water (1 500mL) and compound polyethylene glycol electrolyte plus drinking water (4000mL) were taken orally, respectively in observation group and control group. The basic information, intestinal cleanliness, acceptance of medication, foam formation, pathological changes and adverse reactions were observed and compared between two groups. ResultsThere were no significant differences in Boston score, bubble size and detection rate of colorectal polyps between two groups (P>0.05). In observation group, the patient acceptance for preparation medication doses was higher than that in control group(P<0.05), the incidence of nausea and vomiting was significantly lower than that in control group(P<0.05), and the incidence of dry mouth and fatigue was higher than that in control group (28.37%vs3.69%, χ2=7.862, P<0.05; 10.73%vs3.32%, χ2=3.275, P<0.05). There was no significant differences in terms of abdominal distension, abdominal pain, dizziness and headache between two groups (P>0.05). ConclusionLactulose oral solution is safe, reliable and effective, with few adverse reactions and good patient acceptance in intestinal preparation before colonoscopy diagnosis and treatment.
文章编号: 中图分类号:R574.62 文献标志码:B
基金项目:北京医学奖励金项目(YXJL-2020-1320-0764);刘飞南京市名中医工作室(LF-2019-NJ)
引用文本: