Abstract:Lupus nephritis, Henoch-Schonlein purpura nephritis, hepatitis B virus-associated glomerulonephritis(HBV-GN) and diabetic kidney disease are the most common secondary kidney diseases in China, which are the important causes of end-stage renal failure. Early diagnosis and treatment are particularly important for disease prognosis. The researches have implicated inflammation as a key factor in the occurrence and development of kidney diseases. Neutrophil-to-lymphocyte ratio (NLR) is a new inflammatory marker that has attracted much attention in recent years and has been found to be one of the important predictors of the severity and prognosis of primary kidney diseases. This article reviews the recent advances in the research of NLR in common secondary kidney diseases.