Abstract:Objective To explore the curative effect of action observation therapy and synchronized body weight support training on gait and upper limb function in stroke patients. Methods A total of 110 stroke patients admitted to Beijing Rehabilitation Hospital from August 2020 to March 2022 were selected and randomly divided into observation group and control group (n=55, each). Based on the conventional rehabilitation training in two groups, synchronized body weight support training was given in control group, and action observation therapy was supplemented besides synchronized body weight support training in observation group. Before and after treatment, Montreal Cognitive Assessment (MoCA) Scale, Mini-Mental State Examination (MMSE), Berg Balance Scale (BBS) and Fugl-Meyer Assessment (FMA), modified Barthel index (MBI) and flash-visual evoked potential (F-VEP) were measured and compared between two groups. Results After treatment, MoCA score, MMSE score, BBS score, FMA score of upper-limb and lower-limb and MBI score were significantly increased compared with those before treatment in two groups (P＜0.05), and they were significantly higher in observation group than those in control group (P＜0.05). After treatment, the cadence, stride length and stride speed were significantly increased, and the stride width, percentage of double support phase were significantly decreased in two groups (P＜0.05), and the above-mentioned indicators in observation group were superior to those in control group (P＜0.05). After treatment, F-VEP latency was significantly shortened, and the amplitude was significantly increased in two groups, and the F-VEP latency and amplitude levels in observation group were significantly superior to those in control group (P＜0.05). Conclusion Action observation therapy combined with synchronized body weight support training can effectively improve the cognitive and motor function, the ability of daily living and the abnormal gait and visual electrophysiology of stroke patients.