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中国临床研究英文版:2023,36(2):218-222
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术前营养状态对肝细胞癌肝切除术结局的影响进展
(1. 四川大学华西医院肝脏外科,四川 成都 610041;2. 四川大学华西护理学院,四川 成都 610041;3. 成都中医药大学附属医院乳腺外科,四川 成都 610075)
Influence of preoperative nutritional status on the outcome of hepatectomy for hepatocellular carcinoma
摘要
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Received:October 15, 2022   Published Online:February 20, 2023
中文摘要: 肝细胞癌(HCC)为我国临床常见的恶性肿瘤,首选肝切除术治疗。近十几年随着诊疗技术的进步和肝切除术术式的不断改良和进步,肝切除术适应证范围进一步扩大,越来越多HCC患者获得早期诊断和个性化治疗,存活率大幅度提升。然而HCC患者预后受多种因素影响,有些经过评估认为适合手术的HCC患者即使在接受肝切除术后复发的几率仍较高,预后不理想。营养不良是影响恶性肿瘤患者术后并发症和早期复发的重要因素,已有相关文献将术前营养状态用于预测肿瘤患者预后。HCC患者常伴不同程度营养不良,患者术前营养状态是否影响其临床结局,目前国内尚无系统报告。本文现就术前营养状态对HCC肝切除术结局的影响进展进行综述。
Abstract:Hepatocellular carcinoma (HCC) is a common malignancy in our country, and hepatectomy is the mainstay of treatment for HCC. In recent ten years, the scope of indications for hepatectomy has been further expanded, more HCC patients have received early diagnosis and personalized treatment, thereby the survival rate has been greatly improved. However, because there are many factors influencing the prognosis of patients with HCC, the recurrence rate is high in some patients who were considered suitable for the surgery. Malnutrition is an important risk factor for adverse post-operative outcomes in patients with malignant tumors. It has been described in some relevant literature that preoperative nutritional status has been used to predict the prognosis of patients with tumor. It has not been systematically reported in China that whether the preoperative nutritional status influence the clinical outcomes of HCC patients complicated with various degrees of malnutrition. This article reviews the impacts of preoperative nutritional status on the outcome of hepatectomy for HCC patients.
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